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Updated: Jun 4, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

一个含有强效抗天花病毒药物cidofovir的DNA复合体的溶液结构

Olivier Julien1, James R Beadle, Wendy C Magee

  • 1Department of Biochemistry, University of Alberta, 4-19 Medical Sciences Building, Edmonton, Alberta T6G 2H7, Canada.

Journal of the American Chemical Society
|February 2, 2011
PubMed
概括

抗病毒药物cidofovir (CDV) 集成到DNA中,影响DNA复制和合成. 结构分析显示,CDV是适应的,但降低了DNA双重稳定性,表明动态增加.

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