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Updated: Jun 4, 2026

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
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通过将芳香侧链置于N-糖基化反转转中来稳定蛋白的原始状态

Elizabeth K Culyba1, Joshua L Price, Sarah R Hanson

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|February 5, 2011
PubMed
概括

研究人员发现了一种使用N-糖化稳定蛋白质的新方法. 通过添加特定的氨基酸序列,他们增强了蛋白质折叠和治疗应用的稳定性.

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