通过中央昼夜调节器调节植物免疫反应的时间
Wei Wang1, Jinyoung Yang Barnaby, Yasuomi Tada
1Department of Biology, Duke University, Durham, North Carolina 27708, USA.
Nature
|February 5, 2011
概括
植物免疫反应包括抗性 (R) 基因介导防御和基底防御. 这项研究揭示了由昼夜钟控制的新型基因,将植物免疫力和日常节律联系起来,以增强病原体防御.
科学领域:
- 植物免疫力 植物免疫力
- 循环生物学的日间生物.
- 分子遗传学 分子遗传学
背景情况:
- 植物的免疫反应,特别是抗生物质病原体 (R) 基因介导的防御,对于生存至关重要.
- 在分子层面上,R基因介导的防御和广泛的基底防御机制之间的相互作用尚未完全理解.
- 生物钟在调节植物防御通路中的作用仍然是积极研究的领域.
研究的目的:
- 为了确定参与R基因介导的抗抗在阿拉比多普西斯的菌的新型基因.
- 为了阐明这些防御基因由昼夜调节器的调节控制,CIRCADIAN CLOCK-ASSOCIATED 1 (CCA1).
- 建立植物昼夜节律和免疫反应之间的功能联系.
主要方法:
- 在Arabidopsis中对新型基因突变的表型分析.
- 突变现象型的数值聚类,以确定关键的防御贡献者.
- 通过CCA1.1,研究对防御基因的昼夜调节.
主要成果:
- 编程细胞死亡 (PCD) 被确定为R基因介导耐药性的主要贡献者.
- 在R基因介导的PCD中缺陷的突变体也表现出基底抗性的缺陷,表明了相互连接.
- 新的防御基因由CCA1控制,使植物能够在黎明时预测病原体感染.
结论:
- 植物生理时钟与免疫之间的功能联系已经被揭示出来.
- CCA1暂时控制防御基因,区分它们在基底和R基因介导防御中的作用.
- 循环节调节允许植物根据病原体活动模式优化免疫反应.
相关概念视频
02:00Photoreceptors and Plant Responses to Light
22.5K
Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
22.5K
02:45Biological Clocks and Seasonal Responses
36.0K
The circadian—or biological—clock is an intrinsic, timekeeping, molecular mechanism that allows plants to coordinate physiological activities over 24-hour cycles called circadian rhythms. Photoperiodism is a collective term for the biological responses of plants to variations in the relative lengths of dark and light periods. The period of light-exposure is called the photoperiod.
36.0K
02:19Circadian Rhythms and Gene Regulation
3.4K
The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
3.4K
01:25Cell Signaling in Plants
4.5K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
4.5K