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在骨髓质疏松综合征中准免疫失调

Matthew J Olnes¹, Elaine M Sloand

¹Hematology Branch, National Heart, Lung, and Blood Institute, and Center for Human Immunology, Autoimmunity, and Inflammation, National Institutes of Health, Bldg 10 CRC 3-1341, Bethesda, MD 20892, USA. olnesmj@nhlbi.nih.gov

|February 24, 2011

概括

骨髓质疏松症候群 (MDS) 涉及免疫系统的调节失调. 阿拉姆图祖马布治疗导致了一名泛cytopenic MDS 患者的完全缓解,突出显示了免疫抑制疗法的作用.

科学领域:

血液学血液学血液学
免疫学免疫学免疫学
在瘤学瘤学.

背景情况:

骨髓形综合征 (MDS) 是一种骨髓疾病,具有无效的血液形成和白血病的风险.
免疫系统的调节失调,包括细胞毒性CD8 (((+) 和辅助性CD4 (((+) T细胞,在MDS的发病过程中起作用.
免疫抑制疗法可以改善一些MDS患者的血液反应和存活率.

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