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HMGA1基因和2型糖尿病的功能变异

Eusebio Chiefari1, Sinan Tanyolaç, Francesco Paonessa

  • 1Dipartimento di Medicina Sperimentale e Clinica G. Salvatore, Università di Catanzaro Magna Græcia, Viale Europa, Germaneto Catanzaro, 88100 Italy.

JAMA
|March 3, 2011
PubMed
概括

功能性高流动性A1组 (HMGA1) 基因变异与2型糖尿病 (DM) 有关. 这些HMGA1变异导致胰岛素受体 (INSR) 表达率下降,有助于欧洲血统个体的DM发展.

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