在胚胎和淋巴细胞中,FADD和RIP1之间的功能补充

Haibing Zhang1, Xiaohui Zhou, Thomas McQuade

  • 1Department of Microbiology and Immunology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

Nature
|March 4, 2011
PubMed
概括

与FAS相关的死亡域 (FADD) 蛋白质对胚胎发生和淋巴细胞功能至关重要. 它与RIP1激酶的相互作用出乎意料地调节了编程细胞死亡 (细胞亡) 和亡,影响了发育和免疫反应.

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