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Updated: Jun 23, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

化学免疫球蛋白-T细胞受体蛋白形成功能性受体:对T细胞受体复合体的形成和激活的影响

J Goverman1, S M Gomez, K D Segesman

  • 1Division of Biology, California Institute of Technology, Pasadena 91125.

Cell
|March 23, 1990
PubMed
概括

研究人员使用免疫球蛋白可变区域创建了嵌合式T细胞受体 (Tcr) 链. 这些功能性Tcr复合体与CD3结合并对特定的抗原作出反应,这表明α常数区域可能对Tcr复合体形成不必.

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