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蛋白质结合的序列和结构的计算设计

Deanne W Sammond1, Dustin E Bosch, Glenn L Butterfoss

  • 1Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina 27599-7260, USA.

Journal of the American Chemical Society
|March 11, 2011
PubMed
概括

设计新的蛋白质结合很困难. 研究人员通过计算重新设计了来结合Gα(i1) 蛋白质,通过X射线晶体学验证了新的构造.

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