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拉索框架中的序列多样性:发现了具有多个氨基酸替代的功能微素J25变体

Si Jia Pan1, A James Link

  • 1Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey 08544, USA.

Journal of the American Chemical Society
|March 12, 2011
PubMed
概括

研究人员为增强功能设计了抗微生物Microcin J25 (MccJ25),是一种抗微生物. 尾部区域的突变产生了强大的变异,而环突变影响了活性,揭示了拉索结构功能关系的洞察力.

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