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Updated: Jun 3, 2026

Modified Yeast-Two-Hybrid System to Identify Proteins Interacting with the Growth Factor Progranulin
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增长因子progranulin与TNF受体结合,对小鼠的炎症性关节炎有治疗作用

Wei Tang1, Yi Lu, Qing-Yun Tian

  • 1Department of Orthopaedic Surgery, New York University School of Medicine and NYU Hospital for Joint Diseases, New York, NY 10003, USA.

Science (New York, N.Y.)
|March 12, 2011
PubMed
概括

普格拉努林 (PGRN) 与瘤亡因子受体 (TNFRs) 结合,作为TNFα信号传递的对手. 这一发现为关节炎等炎症性疾病提供了新的治疗途径.

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