慢性胰腺炎 慢性胰腺炎
Joan M Braganza1, Stephen H Lee, Rory F McCloy
1Department of Gastroenterology, Manchester Royal Infirmary, Manchester, UK. jenny.parr@manchester.ac.uk
Lancet (London, England)
|March 15, 2011
概括
慢性胰腺炎是一种进展性疾病,通常是由环境和遗传因素引起的. 新兴的治疗方法,如微量营养素治疗,为管理疼痛缓解以外的症状提供了新的希望.
科学领域:
- 胃肠病学 胃肠病学
- 内部医学 内部医学
- 病理学 病理学 病理学
背景情况:
- 慢性胰腺炎是一种进展性纤维炎症疾病,具有大管和小管形式.
- 病因学涉及环境 (酒精,吸烟,化学品) 和遗传因素 (基因突变,囊性纤维化转膜导电性调节器) 的复杂相互作用.
- 遗传性和自身免疫性疾病是不太常见的原因.
研究的目的:
- 为了总结慢性胰腺炎的多面性质.
- 概述当前和新兴的治疗策略.
- 突出与这种疾病相关的各种临床挑战.
主要方法:
- 关于慢性胰腺炎的现有文献的综述.
- 分析病因因素,包括环境和遗传影响.
- 检查当前和研究中的治疗方式.
主要成果:
- 疼痛是主要的症状,经验上通过止痛药,排水程序或胰腺切除术来管理.
- 类固醇对自身免疫性胰腺炎是有效的;微量营养素治疗对其他形式的治疗有希望.
- ,糖尿病,局部并发症和心理社会问题带来了额外的管理挑战.
结论:
- 慢性胰腺炎需要一个全面的管理方法来解决疼痛,潜在原因和相关并发症.
- 新兴的疗法,如微量营养素校正,为治疗提供了潜在的进步.
- 多学科护理对于管理慢性胰腺炎患者的复杂需求至关重要.
相关概念视频
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