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Updated: Jun 3, 2026

Isolation of Specific Genomic Regions and Identification of Associated Molecules by enChIP
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TERRA 和 hnRNPA1 在端粒单链DNA上编排一个RPA-to-POT1开关

Rachel Litman Flynn1, Richard C Centore, Roderick J O'Sullivan

  • 1Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.

Nature
|March 15, 2011
PubMed
概括

端粒维护涉及DNA复制和通过庇护进行封闭. 异质核核核糖核蛋白A1 (hnRNPA1) 从端粒DNA中取代复制蛋白A (RPA),允许保护端粒1 (POT1) 结合的基因组完整性.

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