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Updated: Jun 3, 2026

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans
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FAS和NF-κB信号调节肺癌对突变EGFR的依赖性

Trever G Bivona1, Haley Hieronymus, Joel Parker

  • 1Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 20, New York, New York 10065, USA.

Nature
|March 25, 2011
PubMed
概括

核因子-kappa B (NF-κB) 途径的抑制增强了EGFR氨酸激酶抑制剂 (TKI) 在EGFR突变肺癌中的疗效. 与EGFR一起准NF-κB可能会改善肺腺癌患者的治疗结果.

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