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Updated: Jun 3, 2026

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
11:06

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

Published on: September 20, 2017

一个全基因组的多维RNAi屏幕揭示了控制MHCII类抗原呈现的途径

Petra Paul1, Tineke van den Hoorn, Marlieke L M Jongsma

  • 1Division of Cell Biology and Centre for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

Cell
|April 5, 2011
PubMed
概括

研究人员确定了主要组织相容性复合体II类 (MHC-II) 表达和运输的关键调节者. 这项研究揭示了控制免疫反应的新途径,以及自身免疫性疾病治疗的潜在目标.

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