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DISC1依赖的切换从原始细胞的增殖到在发育中的皮质中的迁移

Koko Ishizuka1, Atsushi Kamiya, Edwin C Oh

  • 1Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

Nature
|April 8, 2011
PubMed
概括

DISC1蛋白质的酸化作为大脑中的分子开关. 这种开关在皮质形成过程中控制着原始细胞的增殖和神经元的迁移,从而影响精神疾病的易感性.

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