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Updated: Jun 2, 2026

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
08:01

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

Published on: May 30, 2012

Wdr5通过胚胎干细胞核心转录网络调解自我更新和重编程

Yen-Sin Ang1, Su-Yi Tsai, Dung-Fang Lee

  • 1Black Family Stem Cell Institute, Mount Sinai School of Medicine, New York, NY 10029, USA. yen-sin.ang@mssm.edu

Cell
|April 12, 2011
PubMed
概括

WD重复域5 (Wdr5) 通过与Oct4.4相互作用来调节胚胎干细胞的自我更新. 这种相互作用对于维持多能性和将体细胞重新编程成诱导多能干细胞至关重要.

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