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Updated: Apr 30, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
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该AAA+ ATPase 多拉酶调节AMPA受体依赖的突触可塑性和行为

Jianmin Zhang1, Yue Wang, Zhikai Chi

  • 1Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|April 19, 2011
PubMed
概括

AAA+ ATPase 索拉酶通过调节它们的内部化来调节表面AMPA受体 (AMPAR). 删除Thorase会损害AMPAR的去除,影响突触可塑性,导致学习和记忆缺陷.

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