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Updated: May 6, 2026

Identification of Sleeping Beauty Transposon Insertions in Solid Tumors using Linker-mediated PCR
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使用全基因组测序来诊断隐秘的融合瘤基因

John S Welch1, Peter Westervelt, Li Ding

  • 1Department of Medicine, Washington University, St Louis, Missouri, USA.

JAMA
|April 21, 2011
PubMed
概括

全基因组测序发现了急性前兆细胞白血病中隐藏的PML-RARA基因融合. 这种先进的基因组分析在临床相关的时间框架内提供了可操作的见解.

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相关概念视频

Genomics02:02

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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