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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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通过激进SAM酶进行甲基转移的结构基础.

Amie K Boal1, Tyler L Grove, Monica I McLaughlin

  • 1Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208, USA.

Science (New York, N.Y.)
|April 30, 2011
PubMed
概括

激进的S-adenosyl-L-methionine (SAM) 酶RlmN和Cfr甲基化23S核糖体RNA. 这种激进的S-adenosyl-L-methionine (SAM) 酶RlmN和Cfr甲基化23S核糖体RNA. 这种激进的S-adenosyl-L-methionine (SAM) 酶RlmN和Cfr甲基化23S核糖体RNA. 结构研究显示,RlmN使用单个SAM分子和活性位点来执行其复杂的甲基化反应.

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