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选择性生物分子纳米阵列用于并行单分子研究

Matteo Palma1, Justin J Abramson, Alon A Gorodetsky

  • 1Department of Applied Physics & Applied Mathematics, Columbia University, New York, New York 10027, USA. mp2766@columbia.edu

Journal of the American Chemical Society
|May 3, 2011
PubMed
概括

研究人员开发了一种方法,用于精确的纳米控制生物分子在表面上的自我组装. 这使得生物相互作用的高通量,实时,单分子选成为可能.

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...