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Updated: Mar 18, 2026

Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
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由酶催化的 [4+2] 循环添加是氨酸A生物合成的关键步骤

Hak Joong Kim1, Mark W Ruszczycky, Sei-hyun Choi

  • 1Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA.

Nature
|May 6, 2011
PubMed
概括

研究人员确定了SpnF,这是第一个专门的酶,在spinosyn A生物合成中催化了Diels-Alder反应. 这种酶特别加速了环烯环的形成,澄清了天然产品合成的关键步骤.

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