雌激素受体通过抑制大脑炎症.
1Laboratory of Endocrinology and Genomics, CHUQ Research Center and Department of Molecular Medicine, Faculty of Medicine, Laval University, 2705 Laurier Boulevard, Québec, G1V 4G2, Canada.
Cell
|May 14, 2011
概括
雌激素受体β (ERβ) 在多发性硬化症中起着关键作用. 这一途径抑制了炎症,并减缓了小鼠模型中的疾病进展,提供了新的治疗点.
科学领域:
- 神经免疫学 神经免疫学
- 内分泌学 在内分泌学.
背景情况:
- 雌激素受体 (ERs) 与多发性硬化症 (MS) 的病因有关.
- 连接ER与MS病理学的精确分子机制仍然不清楚.
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