从前额叶皮层中神经元的自愿控制来选择性注意
Robert J Schafer1, Tirin Moore
1Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
rhesus 子学会了控制前视场 (FEF) 神经元活动,主要是提高视觉注意力,而不是运动准备. 这表明自愿的神经控制有助于自上而下的注意力,并可能为注意力障碍治疗提供信息.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 灵长类动物的行为
背景情况:
- 操作条件允许在大脑区域中自愿控制神经元活动.
- 这种神经控制与认知功能之间的联系仍然不清楚.
研究的目的:
- 为了研究 rhesus 是否可以自愿控制前额眼野 (FEF) 中的神经元活动.
- 确定操作条件下的FEF活动的认知相关性,特别是与注意力和运动准备的关联.
主要方法:
- 利用操作条件来训练 rhesus 子来控制神经元发射率. 在 FEF 中.
- 在任务期间测量了FEF活动的行为和神经生理相关物.
主要成果:
- 子成功地学会了控制FEF神经元活动.
- 操作驱动的FEF活动主要与增强的选择性视觉注意力有关,而不是眼运动准备.
- 这些注意力效应是未经训练的,在行为和神经生理学上观察到的.
- 选择性注意与自愿的相关,但不是自发的,FEF活动波动.
结论:
- 自愿驱动的FEF神经元活动与自上而下的注意力控制有关.
- 这些发现表明,使用神经反来潜在地治疗注意力障碍的神经生物学基础.
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