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Updated: May 26, 2026

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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酸盐激酶M2是一种PHD3刺激的催氧诱导因子1的协活性剂

Weibo Luo1, Hongxia Hu, Ryan Chang

  • 1Vascular Program, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|May 31, 2011
PubMed
概括

酸激酶M2 (PKM2) 蛋白与缺氧诱导因子1 (HIF-1) 相互作用,增强癌细胞基因活性并改变葡萄糖代谢. 这种相互作用促进瘤生长,并为持续的癌细胞功能创造反循环.

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