早期再极化:与有利的长期结果相关的心电学现象
Jani T Tikkanen1, M Juhani Junttila, Olli Anttonen
1Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, Oulu, Finland. jani.tikkanen@oulu.fi
Circulation
|June 3, 2011
概括
在心电图上早期再极化 (ER) 会增加心律失常死亡的风险. 然而,ER后的特定ST段模式,如运动员中常见的上升类型,表明一种良性变体,并且不会增加这种风险.
科学领域:
- 心脏病学 心脏病学
- 电心电图是指心电图.
- 突然的心脏病死亡.
背景情况:
- 下/侧心电图导线的早期复极化 (ER) 与突然心律失常死亡的风险增加有关.
- 在ER波形之后的ST段特征的变化可能具有预后意义.
研究的目的:
- 在心电图 (ECG) 上研究早期复极化 (ER) 后ST段变异的预后重要性.
- 确定与ER相关的特定ST细分体形态是否可以区分有或没有心律失常死亡风险增加的个体.
主要方法:
- 对年轻运动员 (芬兰,n=62;美国,n=503) 的心电图进行分析,以描述ER后的ST段形态.
- 从一般中年人群 (n=10,864) 中评估ECG,以评估ER相关的ST段变异对失常死亡风险的预后影响.
主要成果:
- 上升/上坡的ST变种是运动员中占主导地位的ER形式 (96%的芬兰,85%的美国).
- 在一般人群中,具有水平/下降ST变异的ER (n=412) 显示出不律性死亡的危险比率增加 (RR 1.43).
- 高幅度的ER (>0.2mV) 与水平/下降的ST变异显著增加了不律性死亡的危险比率 (RR 3.14),而上升的ST变异显示没有增加的风险 (RR 0.89).
结论:
- 与ER相关的ST细分体形态变异对于中年人的心律失常死亡风险分层至关重要.
- 在健康运动员中普遍存在的快速上升的ST段模式似乎是ER的良性变体.
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