在12导电心电图中早期再极化模式的发生率和预后值
Daisuke Haruta1, Kiyotaka Matsuo, Akira Tsuneto
1Department of Clinical Studies, Radiation Effects Research Foundation, 1-8-6 Nakagawa, Nagasaki, Japan. harutad@rerf.or.jp
Circulation
|June 8, 2011
概括
在亚洲人群中,心电图上的早期再极化模式 (ERP) 是常见的. 虽然与心脏病和全因死亡的减少有关,但ERP表明意外死亡的风险增加.
科学领域:
- 心脏病学 心脏病学
- 电心电图是指心电图.
- 公共卫生 公共卫生
背景情况:
- 早期再极化模式 (ERP) 是一个频繁的心电图 (ECG) 发现.
- 其特点是J点的升高和QRS痕/痕在下部/侧面的导线上.
- 关于亚洲人口中ERP发生率和预后的数据有限.
研究的目的:
- 研究亚洲人群中ERP的发病率和长期预后.
- 评估ERP与意外,心脏和任何原因死亡风险之间的关联.
主要方法:
- 在日本长崎,5976名原子弹幸存者的心电图记录的回顾性分析 (1958-2004).
- 定义ERP为≥0.1-mVJ点/ST升高,在≥2个下方/侧面导线中出现隙/隙.
- 利用考克斯分析来评估各种死亡类型的风险.
主要成果:
- 确定了1429例ERP病例 (23.9%的患病率),每10万人/年发生率为715例.
- ERP与意外死亡风险增加 (HR 1.83) 相关,但心脏 (HR 0.75) 和所有原因死亡风险降低 (HR 0.85).
- 特定的形态 (斜纹/纹) 和位置 (下部和侧面的线索) 与更高的意外死亡风险相关.
结论:
- 早期再极化模式与意外死亡的风险增加有关.
- ERP表明心脏病和所有原因死亡率的风险降低.
- 特定的ERP特征预测了更糟糕的预后,强调了需要进一步调查的必要性.
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