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All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
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YAP/TAZ在机械传导中的作用

Sirio Dupont1, Leonardo Morsut, Mariaceleste Aragona

  • 1Department of Histology, Microbiology and Medical Biotechnologies, University of Padua School of Medicine, viale Colombo 3, 35131 Padua, Italy. dupont@bio.unipd.it

Nature
|June 10, 2011
PubMed
概括

细胞通过机械线索感知其物理环境. 该研究确定了YAP/TAZ蛋白质作为关键的核中继器,将这些机械信号转化为细胞反应,影响细胞行为和分化.

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