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Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
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Published on: September 28, 2012

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人类癌症中蛋白质相互作用组分析发现的DNA修复中的cyclin D1的功能

Siwanon Jirawatnotai1, Yiduo Hu, Wojciech Michowski

  • 1Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA.

Nature
|June 10, 2011
PubMed
概括

细胞循环蛋白Cyclin D1意外地通过在损伤部位结合RAD51来帮助DNA修复. 抑制cyclin D1可以治疗视网膜母细胞瘤阴性癌症,扩大其治疗潜力.

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