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抑制葡萄糖脂生物合成会诱导细胞动力学失败

G E Atilla-Gokcumen1, A V Bedigian, S Sasse

  • 1Dana-Farber Cancer Institute and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|June 15, 2011
PubMed
概括

抑制葡萄糖胺合成酶 (GCS) 通过影响血脂质和细胞骨蛋白相互作用来破坏细胞分裂. 这导致在细胞动力学过程中断裂进入失败.

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