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Updated: Jun 1, 2026

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基于反应的光探针用于活细胞中硫化的选择性成像

Alexander R Lippert1, Elizabeth J New, Christopher J Chang

  • 1Department of Chemistry, University of California, Berkeley, California 94720, USA.

Journal of the American Chemical Society
|June 16, 2011
PubMed
概括

研究人员开发了新的光探针Sulfidefluor-1 (SF1) 和Sulfidefluor-2 (SF2),用于在活细胞中选择性成像硫化 (H2S). 这些探测器为研究生物系统中这一重要的信号分子提供了一种新的方法.

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Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...