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在压力下,SIRT6通过激活PARP1来促进DNA修复

Zhiyong Mao1, Christopher Hine, Xiao Tian

  • 1Department of Biology, University of Rochester, Rochester, NY 14627, USA.

Science (New York, N.Y.)
|June 18, 2011
PubMed
概括

在氧化应激过程中,Sirtuin 6 (SIRT6) 蛋白修复DNA双链断裂 (DSB). 它通过修改多基基酶1 (PARP1) 活性来增强修复.

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