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人类组胺H1受体复合体与多克西平的结构

Tatsuro Shimamura1, Mitsunori Shiroishi, Simone Weyand

  • 1Human Receptor Crystallography Project, ERATO, Japan Science and Technology Agency, Kyoto 606-8501, Japan.

Nature
|June 24, 2011
PubMed
概括

与多克西平的组胺H(1) 受体 (H(1) R) 的晶体结构揭示了它在口袋中的深层结合. 这种结构洞察力解释了H(1) R抗剂在治疗过敏方面的选择性.

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