治疗急性术后疼痛的治疗方法
Christopher L Wu1, Srinivasa N Raja
1Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University and School of Medicine, Baltimore, MD 21287, USA. chwu@jhmi.edu
Lancet (London, England)
|June 28, 2011
概括
对疼痛机制的更好理解使得术后疼痛控制得以推进. 新疗法,包括区域止痛药和新药,为患者提供更好的急性疼痛管理结果.
科学领域:
- 疼痛研究和麻醉学.
- 药理学和分子生物学.
- 手术患者的护理.
背景情况:
- 术后疼痛管理得到了改善,但仍然存在挑战.
- 人们越来越了解知觉机制.
- 阿片类药物诱导的过敏症和持续的疼痛是令人担忧的重大问题.
研究的目的:
- 审查了解疼痛机制的进展.
- 探索治疗急性术后疼痛的新疗法.
- 讨论区域止痛药和新的药理学药剂的作用.
主要方法:
- 关于疼痛研究近期进展的文献综述.
- 对新兴的止痛技术和药物的分析.
- 检查急性术后疼痛的治疗方式.
主要成果:
- 了解 nociception 刺激了基因治疗研究.
- 区域性止痛疗法显示出改善患者治疗结果的前景.
- 新的止痛药和治疗方案正在开发中.
结论:
- 疼痛科学的进步为治疗术后疼痛提供了新的途径.
- 多模式方法,包括区域技术和新药,是关键.
- 持续的研究对于优化急性疼痛控制和患者康复至关重要.
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