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生物发光是由域交替机制预测的被捕捉的火虫 luciferase 构造产生的

Bruce R Branchini1, Justin C Rosenberg, Danielle M Fontaine

  • 1Department of Chemistry, Connecticut College, New London, Connecticut 06320, USA. brbra@conncoll.edu

Journal of the American Chemical Society
|June 29, 2011
PubMed
概括

火虫光酶被设计成捕捉一个关键的C域旋转形状. 这种形状,类似于乙-CoA合成酶,允许生物发光,但阻止了露西芬氨基化,揭示了机械洞察力.

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