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Athi N Naganathan1, Modesto Orozco

  • 1IRB-BSC Joint Research Program in Computational Biology, Barcelona Supercomputing Center, Torre Girona, C/Jordi Girona 31, Barcelona 08034, Spain. anarayan@bsc.es

概括

蛋白质的内在障碍和灵活性挑战了传统的结构-功能范式. 这项研究揭示了像NCBD这样的化球状蛋白质利用下坡折叠和结构灵活性进行广泛的伴侣结合,挑战了已有的蛋白质折叠模型.

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