食蛋白质补充剂对血压的影响:一项随机对照试验
Jiang He1, Marion R Wofford, Kristi Reynolds
1Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA. jhe@tulane.edu
Circulation
|July 20, 2011
概括
与碳水化合物补充剂相比,饮食中的大豆或牛奶蛋白摄入显著降低了压缩性血压 (BP) 在患有前高血压或第一阶段高血压的成年人中. 这些蛋白质来源可能有助于预防和治疗高血压.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 临床试验 临床试验
背景情况:
- 观察性研究表明,蛋白质摄入量与血压 (BP) 之间存在联系.
- 高血压仍然是一个重要的全球健康问题.
- 饮食干预对于控制血压至关重要.
研究的目的:
- 为了比较大豆蛋白,牛奶蛋白和碳水化合物补充剂对成人血压的影响.
- 评估蛋白质丰富饮食在管理高血压方面的潜力.
- 为预防高血压提供营养策略的证据.
主要方法:
- 一个随机,双盲,交叉试验,涉及352名患有高血压前期或1期高血压的成年人.
- 参与者每天服用40克大豆蛋白,牛奶蛋白或碳水化合物,每人服用8周,有洗期.
- 使用随机零度血压计测量了静缩和静缩血压.
主要成果:
- 与碳水化合物对照组相比,大豆蛋白补充剂导致静脉血压显著净减少2.0mm Hg (P=0.002).
- 与碳水化合物对照组相比,牛奶蛋白补充剂导致静脉血压显著降低2.3 mm Hg,与碳水化合物对照组相比 (P=0.0007).
- 在大豆和牛奶蛋白干预措施之间没有观察到BP降低的显著差异.
结论:
- 豆类和牛奶蛋白的摄入量有效地降低了患有前高血压和第一阶段高血压的人的缩血压.
- 用大豆或牛奶蛋白代替精制碳水化合物可能是高血压管理的宝贵策略.
- 这些发现支持蛋白质丰富的食物在饮食干预中对心血管健康的作用.
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