控制立体化学信息的传输通过空间在边形Fe4L6子中
Wenjing Meng1, Jack K Clegg, John D Thoburn
1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Journal of the American Chemical Society
|July 28, 2011
概括
研究人员使用基于的配体合成了铁 (Fe) (Fe) (L) . 烯基脊柱上的替代物修饰影响了特定子二聚体的形成,揭示了关于性信息传输的见解.
科学领域:
- 超分子化学 超分子化学
- 协调化学 协调化学
- 有机合成 有机合成
背景情况:
- 铁边铁 (II) 是一种自我组装的协调化合物.
- 子形成的立体化学结果可以受到连接体设计的影响.
- 了解二聚体分布对于控制子特性至关重要.
研究的目的:
- 为了合成和表征一系列的烯基边缘Fe(4) L(6) .
- 为了研究烯基骨干替代对子二聚体形成的影响.
- 分析这些超分子系统中控制着性信息传输的因素.
主要方法:
- 合成Fe(4) L(6) ,使用替代的4,4''-diamino-p-terphenyls,2-formylpyridine和铁(II).
- 使用核磁共振光谱学 ((1) H 和 (13) C 核磁共振光谱) 进行二聚体比的表征.
- 对热力学原理和性信息传输机制的分析.
主要成果:
- 对于母方氨基,所有三种可能的二聚体 (T,S,4,C,3) 对称) 都在几乎相同的数量中形成.
- 在二烯胺骨干上用甲基的替代选择性地有利于特定的异构体:T对称与2.2′′-二甲基二烯胺,S(4) 与2',3',5',6'-四甲基二烯胺,C(3) 与2',5'-二甲基二烯胺.
- 确定了影响金属顶点之间的奇拉信息传输的关键因素.
结论:
- 铁4) L6) 组件的立体化学结果对烯联体的替代模式非常敏感.
- 连接体设计提供了一个强大的工具来控制自组装的二聚体分布.
- 这项研究阐明了协调中的热力学和奇拉信息传输的基本原理.
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