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Updated: May 30, 2026

Residue-Specific Exchange of Proline by Proline Analogs in Fluorescent Proteins: How "Molecular Surgery" of the Backbone Affects Folding and Stability
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RNA模仿绿色光蛋白的绿色光蛋白

Jeremy S Paige1, Karen Y Wu, Samie R Jaffrey

  • 1Department of Pharmacology, Weill Medical College, Cornell University, New York, NY 10065, USA.

Science (New York, N.Y.)
|July 30, 2011
PubMed
概括

研究人员开发了结合光体的RNA体,创造了绿色光蛋白 (GFP) 的""RNA模仿物. 这一突破使得RNA的光标记能够用于生物体中的细胞成像.

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Reporter Genes02:11

Reporter Genes

Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
Commonly used reporter...