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FADD可以预防RIP3介导的上皮细胞死亡和慢性肠道炎症

Patrick-Simon Welz1, Andy Wullaert, Katerina Vlantis

  • 1Institute for Genetics, Centre for Molecular Medicine, University of Cologne, Zülpicher Str. 47a, 50674 Cologne, Germany.

Nature
|August 2, 2011
PubMed
概括

关死亡域 (FADD) 蛋白质可以防止肠道上皮细胞 (IECs) 的编程死亡. 抑制RIP3依赖的IEC亡可以保持肠道屏障的完整性,并预防炎症性肠道疾病.

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