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埃博拉病毒的进入需要胆固醇载体Niemann-Pick C1的输送器

Jan E Carette1, Matthijs Raaben, Anthony C Wong

  • 1Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, Massachusetts 02142, USA.

Nature
|August 26, 2011
PubMed
概括

研究人员确定了对于埃博拉病毒和马尔堡病毒进入细胞至关重要的宿主因素. 在HOPS复合体或NPC1蛋白质中发生的干扰阻断了菲洛病毒感染,提供了潜在的抗病毒标.

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