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Updated: May 11, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

通过低氧诱导因子1控制T (H) 17/T (reg) 平衡

Eric V Dang1, Joseph Barbi, Huang-Yu Yang

  • 1Immunology and Hematopoiesis Division, Department of Oncology and Medicine, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Maryland 21231, USA.

Cell
|August 30, 2011
PubMed
概括

低氧诱导因子1 (HIF-1) 控制T细胞分化,促进T细胞,同时抑制调节性T细胞 (T细胞). 代谢因素影响T细胞命运,为免疫疾病提供潜在的治疗点.

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Generation and Functional Verification of Hypoxia-Sensitive Chimeric Antigen Receptor-T Cells09:12

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