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在心性心力衰竭中练习振荡呼吸:表现为血液动力学对运动反应受损的指标
Ryan M Murphy1, Ravi V Shah, Rajeev Malhotra
1Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Circulation
|August 31, 2011
概括
在心力衰竭 (HF) 中,运动振荡呼吸 (EOV) 与心脏指数降低和运动期间更高的填充压力有关. 这表明EOV可能表明HF患者的血液动力学损伤.
科学领域:
- 心脏病学 心脏病学
- 肺部生理学 肺部生理学
- 运动医学 运动医学
背景情况:
- 运动振荡式通风 (EOV) 是已知的预测器,用于预测心力衰竭 (HF) 的结果.
- 之前的研究缺乏机械洞察力,原因是运动期间侵入性血液动力学和血液气体数据有限.
研究的目的:
- 为了研究EOV和HF患者在运动期间的侵入性血液动力学测量之间的关系.
- 确定EOV的预测因子及其与心脏指数 (CI) 和填充压力的关联.
主要方法:
- 56名HF患者和19名对照人进行了增量心肺运动测试.
- 测量了Fick的心脏输出,填充压力和动脉血液气体.
- 在45%的HF患者中检测到EOV.
主要成果:
- 较高的右心房压力,肺毛细血管压力和较低的心脏指数预测了EOV.
- 低运动心脏指数是EOV的最强预测因素.
- 在患有EOV的HF患者中,运动CI与EOV幅度和周期长度相反相关.
结论:
- 在HF中,EOV与心脏指数降低和运动期间填充压力升高密切相关.
- 在高频率中,EOV可以作为运动诱导的血液动力学损伤的替代标志物.
- 在EOV的HF患者中,西尔德纳菲尔治疗导致EOV幅度和周期长度下降,与CI增加成比例.
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