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Updated: May 5, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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Published on: November 3, 2010

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镜像极端的BMI表型与染色体16p11.2位点的基因剂量相关

Sébastien Jacquemont1, Alexandre Reymond, Flore Zufferey

  • 1Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.

Nature
|September 2, 2011
PubMed
概括

16号染色体上的遗传重复与体重不足有关,与与删除相关的肥胖症形成鲜明对比. 这一发现表明,肥胖和体重不足的基因原因反映在镜像中,影响能量平衡.

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