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Updated: May 29, 2026

Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation
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Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation

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经典蛋白质-铁酸和"Redoxome"的全球蛋白质学评估

Robert Karisch1, Minerva Fernandez, Paul Taylor

  • 1Department of Medical Biophysics, University of Toronto, Toronto M5G 2M9, ON, Canada. rkarisch@uhnresearch.ca

Cell
|September 3, 2011
PubMed
概括

我们开发了蛋白质组学方法来识别和量化所有蛋白质-铁酸酶 (PTP) 和它们的氧化形式 (oxPTP). 这揭示了正常和癌细胞中不同的PTPomes和oxPTPomes,突出显示了新的调控复杂性.

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...