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在C. elegans中通过母性RNA对生殖系基因表达的表观遗传许可

Cheryl L Johnson1, Andrew M Spence

  • 1Department of Molecular Genetics, Collaborative Program in Developmental Biology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

Science (New York, N.Y.)
|September 3, 2011
PubMed
概括

确定性别的基因fem-1的母性RNA转录对于子女的生殖系中适当的基因表达至关重要. 这种母体效应防止了表观遗传沉默,确保了Caenorhabditis elegans的生殖系完整性.

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Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...