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与HLA-DR分子的不变链关联抑制了免疫原性结合

P A Roche1, P Cresswell

  • 1Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710.

Nature
|June 14, 1990
PubMed
概括

不变 (I) 链在它们的运输早期阻止类与人白细胞抗原-DR (HLA-DR) 分子的结合. 然而,成熟的HLA-DR分子有效地结合,保持MHC类I和II分子的独特功能.

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