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Updated: May 29, 2026

Chronic Constriction of the Sciatic Nerve and Pain Hypersensitivity Testing in Rats
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Published on: March 13, 2012

HCN2离子通道在炎症和神经病痛中起着核心作用

Edward C Emery1, Gareth T Young, Esther M Berrocoso

  • 1Department of Pharmacology, University of Cambridge, Cambridge CB2 1PD, UK.

Science (New York, N.Y.)
|September 10, 2011
PubMed
概括

该HCN2离子通道对于启动神经病痛至关重要,它通过驱动 nociceptors中的动作潜能发射来启动神经病痛. 在特定的疼痛感应神经元中删除HCN2可以防止神经损伤后的神经病痛的发展.

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