相关实验视频

Updated: May 29, 2026

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4
06:56

A Flow Cytometry-based Assay to Identify Compounds That Disrupt Binding of Fluorescently-labeled CXC Chemokine Ligand 12 to CXC Chemokine Receptor 4

Published on: March 10, 2018

一个全性激素激素杜素和化学因子受体CXCR4之间的直接相互作用

Jay M Janz1, Yong Ren, Richard Looby

  • 1Anchor Therapeutics, Cambridge, Massachusetts 02142, United States. jjanz@anchortx.com

Journal of the American Chemical Society
|September 13, 2011
PubMed
概括

研究人员开发了一种照片交叉链接方法,以研究卜杜辛如何与G蛋白结合受体 (GPCR) 相互作用. 这项技术证实ATI-2341直接与化学C-X-C型受体4 (CXCR4) 结合,揭示了一种新的全调制机制.

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Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells14:02

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