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用于双重向癌症成像和治疗的细胞特异性,可激活和治疗前药物

Santimukul Santra1, Charalambos Kaittanis, Oscar J Santiesteban

  • 1NanoScience Technology Center, University of Central Florida, 12424 Research Parkway, Suite 400, Orlando, Florida 32816, USA.

Journal of the American Chemical Society
|September 14, 2011
PubMed
概括

研究人员开发了一种新型的叶酸-多克索鲁比结合物,它在进入细胞之前是不活性的. 在细胞内部,谷氨激活结合物,增强光和杀死癌细胞. 这种有针对性的前药物方法改善了药物输送和疗效.

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