风险,临床特征和与儿科心脏手术相关的血栓形成的结果
Cedric Manlhiot1, Ines B Menjak, Leonardo R Brandão
1The Hospital for Sick Children, 555 University Avenue, Toronto, ON, Canada M5G 1X8.
Circulation
|September 14, 2011
概括
儿童心脏手术患者经常出现血栓形成,这是一个严重的并发症,影响恢复和生存. 早期检测和预防策略对于改善这些脆弱儿童的结果至关重要.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心血管外科心血管外科
- 血栓形成的研究研究
背景情况:
- 血栓形成是小儿心脏手术的一个未被认可的并发症.
- 过去的研究并没有在这个患者群体中显著关注血栓形成.
研究的目的:
- 调查心脏手术的儿童中血栓形成的发病率,危险因素,并发症和结果.
- 突出提高意识和管理策略的必要性.
主要方法:
- 对1542次儿科心脏手术的回顾性分析.
- 444 thrombi. 的识别和表征.
- 统计分析以确定风险因素和相关并发症.
主要成果:
- 11%的患者患有血栓形成,其中66%是封闭性,60%是症状性.
- 风险因素包括年轻年龄,较低的氧和度,先前的血栓形成,心脏移植,深度低温循环停止,中枢线持续时间和体外支持.
- 血栓形成与急症监护室/住院时间增加,心脏骤停,重新干预,重新手术和死亡率有关.
- 62%的血栓在长期随访中消失,受位置和血栓特征的影响.
结论:
- 血栓形成是儿科心脏手术中的一个重要问题,影响了大量患者.
- 它与严重的并发症和不良结果有关,包括增加的死亡率.
- 加强警,预防和检测策略对于管理这种队列中的血栓形成至关重要.
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